17 alpha-hydroxyprogesterone aldolasemedical dictionary

<enzyme>

<cell biology> An enzyme of the lyase class that catalyses the cleavage of the bond between carbons 17 and 20 in 17-alpha hydroxyprogesterone to form delta 4-androstene-3,17-dione, an androgen.

It also catalyses the conversion of 17 alpha-hydroxypregnenolone to dehydroepiandrosterone.

Chemical name: 17 alpha-hydroxyprogesterone acetaldehyde-lyase

Registry number: EC 4.1.2.30

(12 Dec 1998)