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medical dictionary


A cell-cycle phase non-specific alkylating antineoplastic agent. It is used in the treatment of brain tumours and various other malignant neoplasms. This substance may reasonably be anticipated to be a carcinogen according to the fourth annual report on carcinogens.

Pharmacological action: antineoplastic agent, alkylating, carcinogens.

Chemical name: Urea, N,N'-bis(2-chloroethyl)-N-nitroso-

(12 Dec 1998)