Creutzfeld Jacob diseasemedical dictionary

<disease>

<virology> Rare fatal pre senile dementia of humans, similar to kuru and other slow viruses.

Method of transmission unknown. Will induce neurological disorder in goats 3-4 years after inoculation with CJD brain extract. Classified pathologically as a subacute spongiform encephalopathy.

See: Prions.

This entry appears with permission from the Dictionary of Cell and Molecular Biology

(11 Mar 2008)