glutathione reductasemedical dictionary

<enzyme>

<cell biology> An FAD containing enzyme, a dimer of 50 kD subunits.

It catalyses the NADP dependent reduction of glutathione disulphide (GSSG) to glutathione (GSH). This is an essential reaction that maintains a GSH:GSSG ratio in the cytoplasm of _500:1.

This entry appears with permission from the Dictionary of Cell and Molecular Biology

(11 Mar 2008)