Herxheimer's reactionmedical dictionary

An inflammatory reaction in syphilitic tissues (skin, mucous membrane, nervous system, or viscera) induced in certain cases by specific treatment with Salvarsan, mercury, or antibiotics; believed to be due to a rapid release of treponemal antigen with an associated allergic reaction in the patient.

Synonyms: Jarisch-Herxheimer reaction.

(05 Mar 2000)