MAB -->
monoclonal antibody
medical dictionary

<immunology, molecular biology> A substance, usually a protein, which can be synthsised in the laboratory in pure form by a single clone (population) of cells.

These antibodies can be made in large quantities and have a specific affinity for certain target molecules called antigens which can be found on the surface of cells and those that are malignant.

Monoclonal antibodies are currently being investigated as a possible form of cancer treatment although their benefit has not be fully proven.

Abbreviation: MoAb

(16 Dec 1997)