Microtubule-associated proteins, may form part of the electron lucent zone around a microtubule. MAP1A and 1B approximately 350 kD) from brain, form projections from microtubules, MAP2A and 2B (270 kD) are also from brain microtubules and form projections. MAP3 (180 kD) and MAP4 (220-240 kD) have been described as co purifying with MAPs 1 and 2. Microtubule-associated protein 2 is associated with axonal processes of vertebrate nerve cells and its presence distinguishes them from dendritic processes. MAP1C is in a separate class, being a motor molecule.
This entry appears with permission from the Dictionary of Cell and Molecular Biology
(11 Mar 2008)
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