SNE -->
subacute necrotizing encephalomyelopathy
medical dictionary

A rare fatal disorder, primarily of children, being both acute and chronic in onset, manifested primarily as brainstem dysfunction, with ataxia, cranial nerve palsies, pseudobulbar palsy, hemi-or quadriplegia, mental deterioration, and involuntary movements; deficiencies of pyruvate dehydrogenase or cytochrome C oxydase have been found in some patients; pathologically, there is widespread symmetric necrosis involving much of the brainstem; these changes are similar to those seen with Wernicke encephalopathy.

Acronym: SNE

(05 Mar 2000)