aspartate transaminasemedical dictionary

<enzyme>

<cell biology> An enzyme of the transferase class that catalyses the reaction of l-aspartate and 2-ketoglutarate to yield oxaloacetate and l-glutamate. The enzyme is a pyridoxal phosphate protein. In the liver the reaction transfers excess metabolic nitrogen into aspartate for disposal in the urea cycle.

Chemical name: L-Aspartate:2-oxoglutarate aminotransaminase

Registry number: EC 2.6.1.1

(12 Dec 1998)