Integral membrane proteins involved in calcium dependent cell adhesion. There are three types, named after their distributions: N cadherin (neural), E cadherin (epithelial) (equivalent to uvomorulin and L CAM) and P cadherin placental). Formed of a 600 amino acid extracellular domain, containing 4 repeats believed to contain the Ca binding sites, a transmembrane domain and a 150 amino acid intracellular domain.

This entry appears with permission from the Dictionary of Cell and Molecular Biology

(11 Mar 2008)

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