citrate (si)-synthasemedical dictionary

<enzyme>

<cell biology> An enzyme of the lyase class that catalyses the condensation of oxaloacetate and the acetyl group of coenzyme a to form citrate and coenzyme a. This is the initial reaction in the tricarboxylic acid cycle.

Chemical name: Citrate oxaloacetate-lyase ((pro-3S)-CH2COO(-)--acetyl-CoA)

Registry number: EC 4.1.3.7

(12 Dec 1998)