A beta-adrenergic blocking agent with brief duration of action.

Pharmacologic action: Short acting beta-blocker with rapid onset. Beta-1 selective at normal doses. Reduces heart rate, myocardial contractility, and blood pressure, but also reduces myocardial oxygen demand.

Uses: Consider use of this beta-blocker for atrial fibrillation and atrial flutter. May also be used for PSVT after using adenosine and verapamil.

Dose: Loading dose: 0.25 - 0.5 mg/kg. Maintenance: 50-100 mcg/kg per min

Potential complications: bradycardia, worsened AV block, hypotension, congestive heart failure, bronchospasm (unusual at normal dose).

Chemical name: Benzene propanoic acid, 4-[2-hydroxy-3-[(1-methylethyl)amino]propoxy]-, methyl ester, hydrochloride.

(15 Mar 2000)

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