familial amyloid neuropathymedical dictionary

<neurology> A disorder in which various peripheral nerves are infiltrated with amyloid and their functions disturbed, an abnormal prealbumin is also formed and is present in the blood; characteristically, it begins during mid-life and is found largely in persons of Portuguese descent. Other rare clinical types occur.

Inheritance: autosomal dominant.

Synonyms: familial amyloidosis, hereditary amyloidosis.

(05 Mar 2000)