fructose 1,6-bisphosphatemedical dictionary

<biochemistry> This key intermediate in glycolysis and gluconeogenesis (a hexose diphosphate) was discovered by Arthur Harden and William Young in 1905.

In the third step of glycolysis, fructose 6-phosphate and ATP are converted to fructose 1,6-bisphosphate and ADP with the aid of phosphofructokinase. In step 4, fructose 1,6 bisphosphate (with the aid of aldolase) is cleaved into duhydroxyacetone phosphate and glyceraldehyde 3-phosphate.

Synonyms: hexosebisphosphatase, hexosediphosphatase.

(08 Mar 2000)

fructosaemia, fructosamine, fructosan, fructose < Prev | Next > fructose-1,6-diphosphatase deficiency

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