glutamate-cysteine ligasemedical dictionary

<enzyme>

<cell biology> One of the enzymes active in the gamma-glutamyl cycle. It catalyses the synthesis of gamma-glutamylcysteine from glutamate and cysteine in the presence of ATP with the formation of ADP and orthophosphate.

Chemical name: L-Glutamate:L-cysteine gamma-ligase (ADP-forming)

Registry number: EC 6.3.2.2

(12 Dec 1998)