glyoxylate cyclemedical dictionary

<biochemistry> Metabolic pathway present in bacteria and in the glyoxisome of plants, in which two acetyl CoA molecules are converted to a 4 carbon dicarboxylic acid, initially succinate.

Includes two enzymes not found elsewhere, isocitrate lyase and malate synthase. Permits net synthesis of carbohydrates from lipid and hence is prominent in those seeds in which lipid is the principal food reserve.

This entry appears with permission from the Dictionary of Cell and Molecular Biology

(11 Mar 2008)