haemoglobinopathymedical dictionary

<disease>

<haematology> Disorder due to abnormalities in the haemoglobin molecule, the best known being sickle cell anaemia in which there is a single amino acid substitution (valine for glutamate) in position 6 of the beta chain. In other cases one of the globin chains is synthesised at a slower rate, despite being normal in structure.

See: thalassaemia.

Origin: Gr. Pathos = disease

American spelling: hemoglobinopathy

(11 Mar 2008)