3-acetyl-1,2,3,4,6,11-hexahydro-3,5,12-trihydroxy- 6,11-dioxo-1-naphthacenyl-3-amino-2,3,6-trideoxy- alpha-l-lyxo-hexapyranoside. An orally administered anthracycline antibiotic. The compound has shown activity against breast cancer, lymphomas and leukaemias, together with potential for reduced cardiac toxicity.

Pharmacological action: antibiotics, anthracycline.

Chemical name: 5,12-Naphthacenedione, 9-acetyl-7-((3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranosyl)oxy)-7,8,9,10-tetrahydro-6,9,11-trihydroxy-, (7S-cis)-

(12 Dec 1998)

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