immunoregulationmedical dictionary

<immunology> The various processes by which antibodies may regulate immune responses. at a simple level, secreted antibody neutralises the antigen with which it reacts thus preventing further antigenic stimulation of the antibody producing clone.

at a more complex level, anti-idiotype antibodies can be shown to develop against the first antibodies in some cases and perhaps further anti-idiotype antibodies against them. This is the major concept of the immunological network theory.

This entry appears with permission from the Dictionary of Cell and Molecular Biology

(11 Mar 2008)