inhibition factor -->
migration-inhibitory factor
medical dictionary

<growth factor>

A soluble, nondialysable factor that is produced by sensitised lymphocytes following exposure to a specific antigen. It inhibits macrophage migration and causes adherence.

It was originally defined on the basis of inhibition of emigration of mononuclear cells from capillary (haematocrit) tubes, more recently a 13 kD protein with migration inhibitory activity has been isolated.

Acronym: MIF

Synonyms: inhibition factor.

(22 Sep 2002)