inhibitory postsynaptic potentialmedical dictionary

The change in potential produced in the membrane of the next neurone when an impulse which has an inhibitory influence arrives at the synapse; it is a local change in the direction of hyperpolarization; the frequency of discharge of a given neurone is determined by the extent to which impulses that lead to excitatory postsynaptic potential's predominate over those that cause inhibitory postsynaptic potential's.

Acronym: IPSP

(05 Mar 2000)