interleukin-9medical dictionary


Cytokine produced by T-cells, particularly when mitogen stimulated, that stimulates the proliferation of erythroid precursor cells (BFU E).

It is thought to be a regulator of haematopoiesis and may act synergistically with erythropoietin. Receptor belongs to haemopoietic receptor super family. It has been shown to enhance the growth of human mast cells and megakaryoblastic leukaemic cells as well as murine helper T-cell clones.

Il-9 is a glycoprotein with a molecular weight of 32-39 that is derived from T-cells, and maps to human chromosome 5.

Acronym: IL-9

(12 Dec 1998)

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