lipoprotein lipasemedical dictionary

<enzyme>

<cell biology> An enzyme of the hydrolase class that catalyses the reaction of triacylglycerol and water to yield diacylglycerol and a fatty acid anion. The enzyme hydrolyzes triacylglycerols in chylomicrons, very-low-density lipoproteins, low-density lipoproteins, and diacylglycerols. It occurs on capillary endothelial surfaces, especially in mammary, muscle, and adipose tissue. Genetic deficiency of the enzyme causes familial hyperlipoproteinaemia type I.

Chemical name: Triacylglycero-protein acylhydrolase

Registry number: EC 3.1.1.34

(12 Dec 1998)