metabolic cooperationmedical dictionary

<cell biology, molecular biology> Transfer between tissue cells in contact of low molecular weight metabolites such as nucleotides and amino acids.

Transfer is via channels constituted by the connexons of gap junctions and does not involve exchange with the extracellular medium. First observed in cultures of animal cells in which radio labelled purines were transferred from wild type cells to mutants unable to utilise exogenous purines.

(27 Jun 1999)