nucleoside qmedical dictionary


(1s-(1 alpha,4 beta,5 beta))-2-amino-5-(((4,5-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-1,7-dihydro-7-beta-d-ribofuranosyl-4h-pyrrolo(2,3-d)pyrimidin-4-one. A modified nucleoside which is present in the first position of the anticodon of tRNA-tyrosine, tRNA-histidine, tRNA-asparagine and tRNA-aspartic acid of many organisms. It is believed to play a role in the regulatory function of tRNA. Nucleoside q can be further modified to nucleoside q*, which has a mannose or galactose moiety linked to position 4 of its cyclopentenediol moiety.

Chemical name: 4H-Pyrrolo(2,3-d)pyrimidin-4-one, 2-amino-5-(((4,5-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-1,7-dihydro-7-beta-D-ribofuranosyl-, (1S-(1alpha,4beta,5beta))-

(12 Dec 1998)