Classically, one of a group of enzymes, now termed oxidoreductases (EC class 1), that bring about oxidation by the addition of oxygen to a metabolite or by the removal of hydrogen or of one or more electrons. Oxidase is now used for those cases in which O2 acts as an acceptor (of H or of electrons); those removing hydrogen are now termed dehydrogenases. For individual oxidases, see the specific names.

Direct oxidase, originally, an oxidase catalyzing the transfer of O2 directly to other bodies; now termed oxygenase.

Indirect oxidase, originally, an oxidase that acts by reducing a peroxide; now termed peroxidase.

Terminal oxidase, the last protein in the electron transport, respiratory chain. In mammals this is cytochrome C oxidase.

(05 Mar 2000)

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