random amplification of polymorphic DNAmedical dictionary

<molecular biology> A term originally invented by polymer chemists to describe a disordered tangle of a linear polymer chain with curved sections. In DNA parlance the random coil refers to the structure that results from melting or other forms of separation of the double helix, i.e. Helix coil transition.

This entry appears with permission from the Dictionary of Cell and Molecular Biology

(11 Mar 2008)