reflux disease, gastro-oesophagealmedical dictionary

The stomach contents regurgitate and back up (reflux) into the oesophagus the food in the stomach is partially digested by stomach acid and enzymes. Normally, the partially digested acid content in the stomach is delivered by the stomach muscle down into the small intestine for further digestion. With oesophageal reflux, stomach acid content refluxes back up into the oesophagus, occasionally reaching the breathing passages, causing inflammation and damage to the oesophagus, as well as to the lung and larynx (the voice box). 10% of patients with gerd develop barrett's oesophagus, a risk fractor in cancer of the oesophagus.

American spelling: reflux disease, gastroesophageal

(12 Dec 1998)

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