signal transductionmedical dictionary

The cascade of processes by which an extracellular signal (typically a hormone or neurotransmitter) interacts with a receptor at the cell surface, causing a change in the level of a second messenger for example calcium or cyclic AMP) and ultimately effects a change in the cells functioning (for example: triggering glucose uptake or initiating cell division). Can also be applied to sensory signal transduction, for example of light at photoreceptors.

This entry appears with permission from the Dictionary of Cell and Molecular Biology

(11 Mar 2008)

signal sequence, signal-to-noise ratio, signal-to-noise ratio < Prev | Next > signal void, signate, signature

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