A derivative of lovastatin and potent competitive inhibitor of 3-hydroxy-3-methylglutaryl coenzyme a reductase (hydroxymethylglutaryl CoA reductases), which is the rate-limiting enzyme in cholesterol biosynthesis. It may also interfere with steroid hormone production. Due to the induction of hepatic ldl receptors, it increases breakdown of ldl-cholesterol (lipoproteins, ldl cholesterol).

Pharmacological action: anticholesteraemic agents, antilipaemic agents, hydroxymethylglutaryl-CoA reductase inhibitors.

(12 Dec 1998)

Simultaneous Peripheral Operation On-Line, simultaneous shipment, SIMV < Prev | Next > Simware, sin, SINA, sinalbin

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