thyroid-stimulating antibodymedical dictionary

<endocrinology, immunology> An antibody generated as an autoantibody that produces a long-acting stimulation of the thyroid and found in Grave's disease and produces thyroid hyperplasia. Human thyroid-stimulating immunoglobulin is a different antibody found in all or nearly all cases of primary thyrotoxicosis and may act by binding to the thyrotropin (TSH) receptor site, causing increased synthesis of thyroglobulin.

(11 Mar 2009)