weal and flare -->
triple response
medical dictionary

<immunology> The vascular changes in the skin in response to mild mechanical injury, an outward spreading zone of reddening flare) followed rapidly by a weal (swelling) at the site of injury.

Redness, heat and swelling, three of the cardinal signs of inflammation, are present.

This entry appears with permission from the Dictionary of Cell and Molecular Biology

(11 Mar 2008)